HEPATITIS B VIRUS SUPPRESSES COMPLEMENT C9 SYNTHESIS BY LIMITING THE AVAILABILITY OF TRANSCRIPTION FACTOR USF-1 AND INHIBITS FORMATION OF MEMBRANE ATTACK COMPLEX: IMPLICATIONS IN DISEASE PATHOGENESIS

Hepatitis B virus suppresses complement C9 synthesis by limiting the availability of transcription factor USF-1 and inhibits formation of membrane attack complex: implications in disease pathogenesis

Abstract Background The complement system functions primarily as a first-line host defense against invading microbes, including viruses.However, the interaction of Hepatitis B virus (HBV) with the complement-components during chronic HBV infection remains largely unknown.We investigated the mechanism by which HBV inhibits the formation of cytolytic

read more

Role of self-sufficiency, productivity and diversification on the economic sustainability of farming systems with autochthonous sheep breeds in less favoured areas in Southern Europe

Traditional mixed livestock cereal- and pasture-based sheep farming systems in Europe are threatened by intensification and specialisation processes.However, the intensification process does not Fall entertaining always yield improved economic results or efficiency.This study involved a group of farmers that raised an autochthonous sheep breed (Oji

read more

Deterioration of autoimmune condition associated with repeated injection of dextranomer/hyaluronic acid copolymer: A case report

A 6-year-old girl underwent ureterocystoneostomy (UCN) because of left flank pain due to delayed onset of ureteral stenosis one and a half years after endoscopic dextranomer/hyaluronic Insulated Beverage Server Lids acid copolymer (Deflux) injection for the treatment of vesicoureteral reflux (VUR).Histopathological examination indicated chronic inf

read more

Light-mediated double-strand DNA cleavage by an alkyldicobalamin

Agents that cause double-strand breaks (DSBs) of DNA via radical formation have been demonstrated to be effective in treating cancer because DSBs result in cellular apoptosis.Light-responsive agents for the treatment of cancer have been of interest for decades because they afford the Oyster ability to spatially control chemical reactions limiting t

read more

Incidence of catastrophic healthcare expenditure and its main determinants in Mexican households caring for a person with a mental disorder

Abstract Background There are few studies on the impact of out-of-pocket mental health care expenditures and sociodemographic factors on the probability of Mexican households to incur catastrophic healthcare expenditures (CHE).Objective The goal of the present study was to estimate the incidence of CHE and its main determinants among the households

read more